Product Overview

1-Decanesulphonic Acid Sodium Salt Anhydrous 99% For HPLC (CAS No. 13419-61-9) is the sodium salt of decane-1-sulphonic acid, an anionic organosulphonate consisting of a linear ten-carbon alkyl chain attached to a sulphonate group. Its combination of a hydrophobic decyl chain and an ionic sulphonate group enables ion-association interactions with positively charged substances in aqueous chromatographic systems. The reagent can influence analyte retention through electrostatic interactions and partitioning effects involving reversed-phase stationary materials.

The HPLC grade is intended for use as an ion-pairing reagent in reversed-phase liquid chromatography, particularly for the separation of basic and cationic compounds. When incorporated into a suitable aqueous-organic mobile phase, sodium decanesulphonate modifies chromatographic interactions involving protonated amines, positively charged nitrogen-containing compounds and other ionic analytes. The anhydrous form provides a defined salt composition for preparing mobile-phase solutions at selected molar concentrations during chromatographic method development and analysis.

Typical Applications

• Preparation of aqueous mobile phases for reversed-phase ion-pair HPLC
• Chromatographic separation of protonated amines and basic organic compounds
• Improvement of retention and selectivity for positively charged analytes
• Ion-pair chromatographic analysis of suitable basic pharmaceutical compounds
• Method development involving alkylsulphonate-modified reversed-phase systems
• Investigation of mobile-phase composition and ion-pairing reagent concentration on analyte retention
• Preparation of defined ion-pairing reagent solutions for chromatographic analytical procedures

Common Synonyms

• Sodium 1-Decanesulphonate
• Sodium 1-Decanesulfonate
• Sodium Decane-1-sulfonate
• Sodium Decanesulphonate
• Sodium n-Decylsulphonate
• Anhydrous Sodium Decanesulfonate

Storage Conditions

Store tightly closed in a cool, dry place, protected from moisture and contamination. Reseal promptly after dispensing to preserve the anhydrous composition and suitability for chromatographic reagent preparation.