Product Overview

Benzyl Alcohol 99.9% GC-HS (CAS No. 100-51-6) is a primary aromatic alcohol containing a hydroxymethyl group attached directly to a phenyl ring. Its aromatic and hydroxyl functionalities provide useful solvating capacity for many compatible organic substances, while its comparatively limited transfer into the vapour phase allows volatile components dissolved in the liquid matrix to be sampled selectively by headspace gas chromatography.

The GC-HS grade is intended for static headspace gas-chromatographic procedures in which solvent-derived volatile background and interfering peaks must be carefully controlled. It is particularly relevant as a high-boiling matrix medium or sample diluent for residual-solvent analysis, solvent-blank preparation, calibration and recovery studies, and compatible methods requiring dissolution of the test material before headspace equilibration. Selection of equilibration, dilution, and sample-treatment conditions remains method-specific because analyte partitioning and recovery depend on the sample matrix and the volatile compounds being determined.

Typical Applications

• Matrix medium or sample diluent in static headspace GC methods for the determination of volatile residual solvents.
• Preparation of solvent blanks for evaluating volatile background, interfering peaks, and system cleanliness.
• Preparation of calibration, spiked, and recovery-test solutions in compatible GC-HS procedures.
• Dissolution of suitable organic samples requiring a comparatively high-boiling headspace matrix.
• Development and verification of headspace methods involving ICH-classified or other specified residual solvents.
• Investigation of analyte partitioning, headspace recovery, equilibration behaviour, and matrix effects.
• Quality-control procedures requiring GC-HS-grade benzyl alcohol as the prescribed sample-preparation medium.

Common Synonyms

• Benzenemethanol
• Phenylmethanol
• Phenylcarbinol
• Phenylmethyl Alcohol
• (Hydroxymethyl)benzene
• α-Hydroxytoluene
• α-Toluenol
• Benzenecarbinol

Storage Conditions

Store in a tightly closed container protected from light in a cool, dry, and well-ventilated area. Minimise prolonged exposure to air and contamination by volatile organic substances that could affect the headspace blank. Close the container promptly after use and use clean, solvent-compatible dispensing equipment to preserve chromatographic cleanliness. During analytical solution preparation, avoid unnecessary prolonged sonication or harsh treatment that could promote formation of volatile degradation products.