Product Overview

Hydrochloric Acid 36.5% For Molecular Biology (CAS No. 7647-01-0) is an aqueous solution of hydrogen chloride, a strong monoprotic acid that dissociates extensively in water to provide hydronium and chloride ions. Its pronounced acidity, water compatibility and volatile nature make hydrochloric acid a fundamental reagent for establishing or adjusting acidic conditions in aqueous chemical and biological systems. Chloride acts primarily as a counter-ion in these solutions, while the protonating capacity of hydrochloric acid enables controlled acidification and neutralisation reactions during laboratory reagent preparation.

The Molecular Biology grade is intended for preparation and adjustment of reagents, buffers and aqueous systems used in molecular and biochemical research where a controlled source of hydrochloric acid is required. Typical uses include pH adjustment of molecular-biology solutions, preparation of acidic buffers and reagent systems, and acidification steps associated with biomolecule processing. The defined concentrated solution form also provides a convenient starting reagent for preparing lower-strength hydrochloric acid solutions required in laboratory protocols, provided the resulting working concentration is established by the specific procedure.

Typical Applications

• Adjustment of pH in molecular-biology and biochemical buffer systems.
• Preparation of acidic buffers and reagent solutions used in biomolecular research.
• Preparation of lower-strength hydrochloric acid solutions for laboratory procedures.
• Acidification of aqueous samples and reaction mixtures where hydrochloric acid is specified.
• Preparation of molecular-biology reagents requiring controlled acidic conditions.
• Acid-treatment and hydrolysis procedures involving biological or biochemical materials where hydrochloric acid is part of the established method.
• General biochemical and molecular-biology research requiring a concentrated hydrochloric acid reagent.

Common Synonyms

• Hydrogen Chloride
• Hydrogen Chloride Solution
• Hydrochloric Acid Solution
• Hydrochloric Acid
• Aqueous Hydrogen Chloride
• Muriatic Acid

Storage Conditions

Store tightly closed in a cool, well-ventilated area and protect the solution from excessive heat and unnecessary exposure to air to minimise evaporation of hydrogen chloride and changes in solution composition. Maintain clean handling conditions and promptly reseal the container after dispensing to limit contamination and preserve the stated concentration for subsequent reagent and buffer preparation.