Product Overview

Silica Gel 60-200 mesh For Column Chromatography (CAS No. 112926-00-8) is an amorphous porous silica adsorbent supplied over the relatively broad 60-200 mesh particle range. Polar silanol groups on the silica surface provide adsorption sites for analytes, with retention influenced by functional-group polarity, solvent competition and the extent of surface interaction. The broad particle distribution gives this catalogue form a different packing profile from narrower mesh fractions.

The Column Chromatography product form is intended for versatile preparative and gravity-column separations where a broad silica particle range is acceptable. It can support routine purification and fractionation across varied sample loads and column configurations, while actual flow and efficiency remain packing- and method-dependent.

Typical Applications

• Routine gravity-column purification of organic reaction products.
• Preparative separation of mixtures by polarity.
• Fractionation of natural extracts and multicomponent samples.
• Adsorptive cleanup before further chemical or instrumental analysis.
• Step-gradient and solvent-gradient normal-phase separations.
• General column-method development requiring a broad silica mesh distribution.

Common Synonyms

• 60-200 mesh silica gel
• Column chromatography silica gel
• Chromatographic silica gel
• Amorphous silica gel
• Silica gel

Storage Conditions

Store tightly closed and protected from humidity to maintain consistent silica surface activity. Avoid exposure to organic vapours, oils, dust and other contaminants that may adsorb strongly and interfere with subsequent chromatographic separation.