Product Overview

Water LC-MS (CAS No. 7732-18-5) is high-purity water intended for liquid chromatography–mass spectrometry, where ionic, organic and non-volatile contamination can contribute directly to detector background, ion suppression, adduct formation and source deposits. As a major component of reversed-phase mobile phases, water quality can influence chromatographic retention as well as electrospray or other atmospheric-pressure ionisation response.

The LC-MS grade is intended for mass-spectrometric mobile phases, sample diluents, extraction solutions, blanks and preparation of volatile buffers and modifiers. Its technical relevance centres on maintaining low ionic and organic background during chromatographic separation and mass-spectrometric ionisation.

Typical Applications

• Aqueous component of LC-MS mobile phases.
• Preparation of LC-MS sample diluents.
• LC-MS blank and background evaluation.
• Preparation of volatile-buffer and modifier solutions.
• Extraction and sample preparation before LC-MS.
• Method development involving control of ionic and organic background.

Common Synonyms

• Aqua
• Distilled H₂O
• Dihydrogen monoxide
• Dihydrogen oxide
• Oxidane

Storage Conditions

Keep tightly closed and protect from ionic, organic, particulate and microbiological contamination. Use dedicated LC-MS-clean dispensing practices to minimise introduction of species that can affect ionisation or generate background signals.